Best NFL picks and predictions for Week 10

Best NFL picks and predictions for Week 10

After the Baltimore Ravens took down the New England Patriots on Sunday Night Football, NFL fans out there learned right away that no team is invincible. And with 13 games on the schedule for Week 10, will more upsets be on the way?

There are some outstanding games on the dockets, none bigger and better than the NFC West showdown between the 8-0 San Francisco 49ers and 7-2 Seattle Seahawks. The 49ers' defense is stout, but Seattle's offense is led by MVP-candidate Russell Wilson and superstar receiver Tyler Lockett. Get ready for a battle. 

Elsewhere, the Cowboys and Vikings will square off in what figures to be a monster showdown, which could very well affect the Super Bowl odds for the two teams. We cover those games and more in this Week 10 preview. 

Los Angeles @ Oakland: 7/11/19 @ 8:20 PM ET

The week's action will kickoff with a showdown in Oakland betwen the Chargers and Raiders. Straight up, these fanbases hate one another, and the players share the same emotions. This will be a classic AFC West tilt. 

Coming off a big win over the Green Bay Packers, the Chargers are one-point favorites leading up to the meeting in Oakland. The offense looked solid on Sunday, with Melvin Gordon posting two touchdowns. Meanwhile, Nick Bosa and the defense held Aaron Rodgers in check and will hope to do the same to Derek Carr.

Oakland Raiders To beat the LA Chargers
William Hill

The Raiders are 4-4 on the year, while L.A. is 4-5. The Chargers may be 1-point favorites, but Oakland has proven they can be a tough team to beat at home. For our NFL picks, we're going with the Raiders. 



Week 10 parlay free pick: Chiefs + Colts + Packers

Parlays can always be a bit tricky, especially when you must depend on multiple teams to be victorious or cover the spread. In Week 10, though, there are some favorable matchups for fans to take advantage of. 

Our parlay opens with the Chiefs covering the four-point spread on the road against the Titans, who have turned to Ryan Tannehill as their starting quarterback. Keep in mind Patrick Mahomes is scheduled to return to the field this week after missing the past two weeks with a dislocated kneecap for KC. 

In addition to that game, we also like the Colts winning straight up at home against the miserable Dolphins, plus the Packers getting back on track at home against the Carolina Panthers. Aaron Rodgers had a day to forget against the Chargers in Week 9. No chance he has back-to-back rough weekends. 

• Chiefs -4 (1.91) over the Titans
• Colts moneyline (1.21) over the Dolphins
• Packers moneyline (1.45) over the Panthers

Sports Interaction (SIA) odds are subject to change - Connect below for current prices.

KC + IND + GB Over TEN + MIA + CAR
Sports Interaction


Minnesota @ Dallas: 10/11/19 @ 8:20 PM ET

The second-best game of the week no question has to be the Sunday Night Football tilt between the Minnesota Vikings and Dallas Cowboys.

If you like high-octane offenses, this will be one to watch. 

Kirk Cousins vs. Dak Prescott at quarterback. Dalvin Cook and Ezekiel Elliott at running back, while Stefon Diggs and Amari Cooper will highlight the wide receiver battle? Yup, this has the makings to be a total shootout. 

Dallas Cowboys To beat the Minnesota Vikings

The Cowboys, fresh off an easy win on the road against the Giants, are 3-point favorites, with 1.60 NFL odds for the moneyline leading up to this one. We don't think they'll cover the spread, but we are going to pick them to take down the Vikings in Arlington. 

Seattle @ San Francisco: 11/11/19 @ 8:15 PM ET

The storylines truly are endless for this upcoming battle, but when the 49ers and Seahawks square off, you know it's going to be something you don't want to miss. 

Week 10 will be more of the same, as the Seahawks will look to hand the 49ers their first loss in 2019. It's been nothing but smooth sailing for Jimmy Garoppolo and Co., who are a perfect 8-0. 

They'll enter Monday Night Football as six-point favorites against Seattle. Touchdown favorites? That seems pretty dang high, and this one should be a backyard brawl. 

Seattle Seahawks To cover the spread against SF

While the 49ers could very well improve to 9-0, Seattle is to tough to be hammered on. We're taking Seattle to cover the spread.