Bills vs. Jets Predictions, Picks, And Odds (11/15/26)

Buffalo Bills quarterback Josh Allen (17) runs onto the field before the game against the New York Jets at Highmark Stadium.

Buffalo’s league-leading scoring production gives us a reason to consider Bills -7.5 as our Bills vs. Jets prediction , though laying more than a touchdown on the road leaves little room for a close finish. The Bills visit the Jets at MetLife Stadium in East Rutherford on Sunday, Nov. 15 at 1:00 p.m. ET for Week 10 of the NFL regular season.

As always, compare prices at Canadian NFL betting sites before locking in a wager.

Bills vs. Jets Prediction

Buffalo Bills -7.5: We’re considering Buffalo on the full-game spread. The Bills lead the NFL with 32 points per game, scoring 256 through eight regular-season outings. New York has scored 182 through nine, averaging 20.22. That offensive contrast gives Buffalo a route to building a margin rather than simply finding a way to win.

The Bills are 4–0 away from home this regular season, while the Jets are 1–3 at home. Buffalo has also won eight of the past 10 regular-season meetings, spanning Nov. 14, 2021, through Jan. 4, 2026. Seven of those eight victories came by at least eight points. It’s a limited historical run, but the margins are relevant when this wager requires more than a touchdown separation.

Buffalo’s defence supplies the clearest reason for caution. The Bills won 33–30 at Las Vegas and 37–34 at the Rams in two of their last five regular-season games. Another afternoon spent trading touchdowns could leave New York inside the number, even in defeat.

Bills vs. Jets Odds

MarketOdds
Bills moneyline-430
Jets moneyline+335
SpreadBills -7.5 (-105), Jets +7.5 (-115)
Game totalOver 50.5 (-118), Under 50.5 (-102)
Odds courtesy of bet365.

About the Bills (7-1 SU, 6-2 ATS, 5-3 o/u)

Buffalo extended its regular-season winning streak to four games by beating Minnesota 23–6. The Bills generated 339 total yards, including 134 on the ground, and controlled possession for 42:32. James Cook carried 31 times for 107 yards and a touchdown, giving the offence a way to keep moving without relying entirely on Josh Allen’s arm.

Cook described it as a “grind-it-out game” afterward. “We stuck with it, stuck with it. Then eventually we broke them.” That patience offers a useful path against New York: sustained possessions can wear down the defence and limit the Jets’ opportunities to answer.

Head coach Joe Brady wants the same persistence on Sunday. “You hope as the game continues on that those two-yard runs can become seven; you have to stick with it,” he said. Early resistance alone is unlikely to persuade Buffalo to abandon the ground game, judging by that approach.

Through eight regular-season games, Cook has 814 rushing yards and eight rushing touchdowns. Allen has thrown for 2,027 yards and 12 touchdowns, adding nine rushing scores. Buffalo can finish drives through either player.

About the Jets (2-7 SU, 4-5 ATS, 4-5 o/u)

New York has lost four consecutive regular-season games, most recently falling 35–12 at Kansas City after defeats against Las Vegas, Miami and New England. The Jets produced 229 total yards against the Chiefs and allowed five sacks. Geno Smith threw for 165 yards without a touchdown.

Keeping possessions alive and finishing them remain pressing problems. New York has converted 40 of 113 third downs this regular season and scored touchdowns on 11 of 27 red-zone opportunities. Settling for field goals or surrendering the ball after a short series would make it difficult to answer Buffalo’s offence.

Aaron Glenn took over defensive play-calling duties this season and has acknowledged the difficulty of balancing that responsibility with overseeing the entire team. On Nov. 9, he said, “We have not played really good defense the last couple of weeks.”

“I’m looking at everything and I’m looking at ways for us to improve,” Glenn said. “Whatever that is for us to get better, you can best believe I’ll make those changes. I’m not saying that is going to be the change, but I’m looking at everything.” His comments left a play-calling change as a possibility, not an announced handover for Sunday.

Key Injuries

Buffalo lists receiver Joshua Palmer as out with a hamstring injury.

New York lists receiver Arian Smith as out with a knee injury and Garrett Wilson as questionable with a concussion. Wilson’s participation remains uncertain. He has 43 receptions for 527 yards and three touchdowns through eight regular-season games, making his status particularly important to the Jets’ chances of keeping pace.

Weather

Forecasts are calling for temperatures around 9 C and sunny skies on Sunday afternoon at MetLife Stadium. Winds will be light and won’t play a factor.

  • Ty Johnson has recorded over 15.5 receiving yards in four straight games and in five of six this season. He’s -110 to eclipse that number again on Sunday.
  • James Cook has scored a touchdown in seven straight games and is -160 to find pay dirt again this week.
  • Tyler Bass has exceeded 8.5 kicking points in four straight games and is -120 to beat that number on Sunday.
  • Greg Rousseau has recorded a sack in back-to-back games and in six of his last 10 dating back to last season. He’s +115 to get a sack.