Premier League Soccer Odds: Manchester City vs Fulham Best Bet

Manchester City vs Fulham odds spotlight a Premier League mismatch ripe for betting value, as Pep Guardiola’s title-chasing machine hosts a scrappy Fulham side desperate for points. This Premier League soccer best bet preview uncovers the top pick with key matchup stats, recent form analysis, and odds edges—ideal for locking in your wager ahead of kickoff in this one-sided affair.

Our best bet for Wednesday’s Premier League clash between Manchester City and Fulham is Manchester City to win and both teams to score at +175 odds (bet365).

Manchester City vs Fulham best bet

• The last time Manchester City and Fulham met in the Premier League was also scheduled as a midweek fixture. The December fixture ended with nine goals scored as City registered five strikes and Fulham hit four. 
• Fulham have only failed to score in four of 25 Premier League matches this season. That’s impressive and ranks them level with Liverpool and Manchester City in this metric, and just one behind Arsenal (3) and Man United (3).
• Only 42% of City’s games at The Etihad Stadium have witnessed ‘both teams to score – yes’ in 2025/26, which is the lowest strike-rate in this market in the Premier League. Still, by contrast, Fulham’s return for both sides scoring (67%) ranks nearer the highest in the division away from home.
• With Manchester City earning an invaluable three points at Anfield, something they often fail to do at that venue, this squad should be buoyed and ready to push on with their title charge. At home, Pep Guardiola’s side should have enough to edge out this travelling Fulham outfit.

Manchester City vs Fulham match context

• Pep Guardiola’s side are battling to keep pace with Arsenal in the Premier League title race. The Gunners have been at the top of the table since matchday seven and are six points ahead of City, meaning they have a clear advantage. 
• Back-to-back defeats has seen Fulham drop to 10th. Their last away game was a 3-2 defeat at Old Trafford. Marco Silva will be hoping his side can fare better in their latest trip to Manchester, but their record at the Etihad is poor. 
• As you’d expect, Manchester City are the clear favourites for this game. Although this isn’t the best City team of Pep’s tenure, their home form is still formidable, particularly in the league, so a Fulham win would be a shock, as well as a huge blow for City’s title chances.

Manchester City vs Fulham odds analysis

• The Manchester City vs Fulham odds are heavily skewed towards the hosts. City’s 1×2 market price implies a 73% chance of victory, while Fulham’s win odds suggest only a 14% probability of an away triumph. Fulham are the biggest-priced underdogs on the Premier League coupon ahead of the midweek round of top-flight fixtures.
• The Asian handicap line is set at Manchester City -1.25. For pro-City bettors, a win by two or more goals returns full profit. If the home team wins by exactly one goal, half stakes are returned. Alternatively, a draw or Fulham win ensures the Fulham +1.25 Asian handicap wins. City have won eight of 12 home matches by at least two goals in the Premier League this season, something to bare in mind for any punters considering Fulham in this market.
• The Asian goal line sits at over/under 3.0 goals. Over 3.0 requires at least four goals to pay out in full, while exactly three goals ensure all stakes on both sides of the 3.0 goal line are refunded. Two goals or fewer means under 3.0 bettors are paid in full.
• Manchester City’s Erling Haaland has scored seven goals in seven appearances against Fulham in Premier League action. Therefore, it’s unsurprising that the Norwegian leads the anytime goalscorer market as he typically does ahead of each matchday in the division. Haaland is the only player priced at odds-on in the goalscorer markets (-225).