The NBA has officially announced a few of the marquee matchups and key events of the 2026-27 regular season. Below, we’ve provided the latest NBA opening night odds and Christmas Day betting lines so you can see who’s set to square off in these can’t-miss showdowns, along with early predictions on how each matchup unfolds.
Don’t wait, check out these opening NBA odds and head to your favourite NBA betting site to place your first bets of the 2026-27 season on all the biggest basketball games of the year.
NBA Opening Night Odds
| Matchup | Moneyline Odds | Point Spread Odds | Point Total Odds |
| DET Pistons @ BOS Celtics | +125/-150 | +2.5 (-105)/-2.5 (-115) | O/U 224.5 (-110/-110) |
| PHI 76ers @ NY Knicks | +135/-160 | +3.5 (-110)/-3.5 (-110) | O/U 229.5 (-110/-110) |
| OKC Thunder @ SA Spurs | +100/-120 | +1.5 (-110)/-1.5 (-110) | O/U 229.5 (-110/-110) |
Odds Provided by bet365
Pistons vs. Celtics
Set to kick off the 2026 NBA opening night odds with a clash between the first- and second-placed squads in last year’s Eastern Conference, the Detroit Pistons will travel to Massachusetts to take on the Boston Celtics at TD Garden. Cade Cunningham and co. will look to start the year off strong as they take on a new-look Boston Celtics squad without Jaylen Brown, in a matchup that could help provide an early look at each teams’ ceiling in 2026-27.
Even with out the services of Brown, I firmly believe that Jayson Tatum has a strong team built around him and will be enough to best the Pistons, starting off the season with a home victory for the Celtics.
Way too Early Pick: Celtics -2.5
76ers vs. Knicks
One of the biggest blockbuster matchups to begin an NBA season ever, the latest superteam in the league will take on the defending NBA Champions as the LeBron James-led Philadelphia 76ers take on the New York Knicks in Madison Square Garden. As The King and his star-studded cast make their debut on the hardwood, the Knicks will look to prove they’re still the team to beat in a highly anticipated showdown.
Don’t be late to the party, believe in the hype of the new-look Sixers and back them to pull off the upset win, spoiling the Knicks banner night, and starting their new era off with victory.
Way too Early Pick: 76ers ML
Thunder vs. Spurs
In a rematch from the 2026 Western Conference Finals, the latest chapter in the league’s hottest rivalry will be written as Shai Gilgeous-Alexander and the Oklahoma City Thunder aim to get revenge over Victor Wembanyama and the San Antonio Spurs. With legitimate bad blood shared between these two contenders, expect a fiery face-off in the NBA Opening Day nightcap as this clash goes down to the wire.
While it was the Spurs who edged out the Thunder in seven games in the 2026 NBA Playoffs, back the Thunder to get the upper hand over their opponents, securing an underdog win on the road to open their 2026-27 campaign.
Way too Early Pick: Thunder ML
NBA Christmas Day Odds
| Matchup | Moneyline Odds | Point Spread Odds | Point Total Odds |
| SA Spurs @ NY Knicks | +100/-120 | +1.5 (-110)/-1.5 (-110) | O/U 229.5 (-110/-110) |
| MIA Heat @ BOS Celtics | +165/-200 | +5.5 (-115)/-5.5 (-105) | O/U 229.5 (-110/-110) |
| PHI 76ers @ LA Lakers | +100/-120 | +1.5 (-110)/-1.5 (-110) | O/U 234.5 (-110/-110) |
| OKC Thunder @ MIN Timberwolves | -160/+135 | -3.5 (-110)/+3.5 (-110) | O/U 229.5 (-110/-110) |
| DEN Nuggets @ GS Warriors | -130/+110 | -1.5 (-115)/+1.5 (-105) | O/U 233.5 (-110/-110) |
Odds Provided by bet365
Spurs vs. Knicks
Set for a rematch of the 2026 NBA Finals to kick off the NBA Christmas Day schedule, the clash between the Spurs and the Knicks promises a playoff atmosphere at the Mecca. After coming up short in the NBA Finals last season ago, look for the Spurs to get their get-back as they spoil Christmas Day for New Yorkers everywhere, taking the upset road victory.
Way too Early Pick: Spurs ML
Heat vs. Celtics
There’s going to be no shortage of eyeballs drawn to this Christmas Day clash as Giannis Antetokounmpo and the Miami Heat travel North to take on the Celtics. While the Heat have plenty of expectations set for them with the former two-time MVP Giannis now at the helm, they still are incredibly limited in their total level of play and depth. Because of this, back the Celtics to take care of business at home and take the win on Xmas Day.
Way too Early Pick: Celtics ML
76ers vs. Lakers
In his first return to the team, he won the 2020 NBA Championship with LeBron, and the 76ers will take on the Los Angeles Lakers live from the Crypto.com Arena. With there sure to be plenty of mixed emotions in James’ return to LA, look for his new squad to get the better of Luka Doncic and Austin Reaves in a high-scoring shootout.
Way too Early Pick: 76ers ML + Over 234.5 Points
Thunder vs. Timberwolves
SGA and the Thunder are set to travel to chilly Minneapolis, Minnesota, as they take on the new-look Timberwolves on Christmas Day. While the NBA world continues to grow gradually more excited for the debut of LaMelo Ball next to Anthony Edwards in the T-Wolves backcourt, look for the Thunder to enter hostile territory and take the win, silencing the hype as they aim to secure another top finish in the Western Conference.
Way too Early Pick: Thunder -3.5
Nuggets vs. Warriors
Capping off the NBA Christmas slate with a head-to-head clash between all-time greats, Nikola Jokic and the Denver Nuggets will go toe-to-toe with Stephen Curry and the Golden State Warriors. As both teams hope to make some noise out West this season, expect a lopsided victory for the Nuggets as their depth and star power shine over an aging Steph Curry and a mediocre Warriors roster.
Way too Early Pick: Nuggets -1.5
