Yankees vs. Blue Jays Prediction, Picks, And Odds (6/12/26)

Toronto Blue Jays designated hitter George Springer (4) hits a single against the New York Yankees during the first inning at Yankee Stadium.

The AL East rivalry heats up once again Friday night, and this Yankees vs. Blue Jays prediction focuses on a matchup that could turn into an offensive showcase at Rogers Centre. Both teams enter the series opener trending toward high-scoring games, with the Yankees riding a four-game winning streak and Toronto hoping to capitalize on favourable hitting conditions at home. The Blue Jays have already had success against Ryan Weathers this season, and with warm weather expected and the dome likely open, the stage is set for plenty of offence.

Yankees vs. Blue Jays prediction

Blue Jays team total over 3.5 runs: -125 @ BET99

Blue Jays over 3.5 runs

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-125

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The Blue Jays are in a good position to produce some runs against Weathers and the Yankees on Friday night in this series opener.

Toronto managed five runs on seven hits less than a month ago against Weathers in a 7-6 loss to New York. Both George Springer and Ernie Clement went deep at Yankee Stadium against the southpaw in that contest.

Additionally, Weathers is in a funk right now, allowing exactly five runs in three of his last four starts.

Toronto is averaging 4.36 runs per game at Rogers Centre this season, but seasoned bettors know that when the hot weather arrives and the retractable dome is open, the ball carries very efficiently at the venue, typically leading to higher-scoring games. With hot and humid weather expected in Toronto on Friday night, you can bet the dome will be open, making the conditions ideal for offence.

Always look for the most favourable MLB odds at the best MLB betting sites before locking in any wagers on our Yankees vs. Blue Jays prediction.

Greg’s Blue Jays predictions are 19-10-2 for +7.78 units this season.

Yankees vs. Blue Jays odds

Yankees moneyline odds-105
Blue Jays moneyline odds-115
Run line oddsBlue Jays -1.5 (+175), Yankees +1.5 (-210)
Game totalOver 8 runs (-105), Under 8 (-115)
Date/timeJune 12, 7:37 p.m. ET
Odds courtesy of bet365.

Betting the Yankees (41-26 SU, 34-33 ATS, 30-34-3 o/u)

The Yankees enter this series tied for the top spot in the AL East with the Tampa Bay Rays.

New York is riding a four-game winning streak into action Friday night after taking all three of its games with the Cleveland Guardians earlier this week.

Yankees pitchers have been incredible this season, holding a combined 3.27 ERA (second in the majors) and a 1.16 WHIP (also second in MLB). They’ve also allowed the least home runs (57) in all of baseball.

Offensively, the team is averaging a hearty 5.1 runs per game (fourth in the majors), although the loss of slugger Aaron Judge for at least the next month due to a rib injury is surely going to hamper the team’s ability to score runs.

Betting the Blue Jays (33-36 SU, 33-36 ATS, 36-32-1 o/u)

The Blue Jays continue to hover around the .500 mark as they wait for key reinforcements to come off the injured list. Alejandro Kirk and Shane Bieber should be returning to the lineup shortly, which should give the bruised and battered club a major boost.

Toronto dropped two of three games to the Philadelphia Phillies earlier this week after taking two of three from the Baltimore Orioles last weekend.

The team continues to struggle offensively, averaging just 4.1 runs per game (21st in the majors). Vladimir Guerrero Jr., the team’s biggest power threat, is still stuck on just three home runs on the season, although he owns own a decent .740 OPS and solid .375 OBP.

Probable starting pitchers

New York: LHP Ryan Weathers (2-4, 3.86 ERA, 1.16 WHIP, 10.16 K/9)

Weathers is not in good form right now after allowing five runs in each of his last two starts against the Boston Red Sox and Athletics. He also allowed five runs in his May 18 start against Toronto over 5 1/3 innings while striking out seven batters.

Bettors should know that Weathers has interesting reverse splits for a southpaw, as left-handed hitters are raking him this season, slashing .304/.339/.411 with a .750 OPS.

He’s also been dreadful across his eight night starts this season, owning a 5.91 ERA while allowing a .250 opponents’ batting average. The lefty has been incredible in four day starts, recording a 0.66 ERA while holding opponents to a .198 batting average.

Toronto: RHP Trey Yesavage (2-3, 3.16 ERA, 1.17 WHIP, 9.28 K/9)

Yesavage is coming off his worst start of the season after allowing six runs on five hits to the Baltimore Orioles last Friday.

However, he was spectacular in his May 20 start against New York, holding the Yankees scoreless over six innings while allowing just two hits. He struck out eight Yankees in that outing.

Yesavage’s splitter has been dominant this season, holding the opposition to a .152/.199/.196 slash line with a 42.6% whiff rate.

Notable injuries

The following players are on the injured list for New York:

  • C Austin Wells (head)
  • P Clarke Schmidt (elbow)
  • P Max Fried (elbow)
  • OF Aaron Judge (rib)
  • OF Jasson Dominguez (shoulder)
  • DH Giancarlo Stanton (calf)

The following players are on the injured list for Toronto:

  • P Shane Bieber (elbow)
  • OF Addison Barger (elbow)
  • C Alejandro Kirk (thumb) – could be activated for this game
  • P Yimi Garcia (elbow)
  • P Joe Mantiply (knee)
  • P Jose Berrios (elbow)
  • P Cody Ponce (knee)
  • OF Anthony Santander (shoulder)
  • P Bowden Francis (elbow)

OF Daulton Varsho is day-to-day with a wrist injury.

Weather

Forecasts are calling for warm temperatures around 24 C and clear skies in Toronto, so it should be an outdoor ballgame. Winds will blow from left field to right field at 14 mph.

  • These teams split a four-game series in New York back in May.
  • The over is 7-3-1 in New York’s last 11 games.
  • The over is 9-2-1 in Toronto’s last 12 games.
  • The Blue Jays are just 9-11 SU against AL East opponents this year.
  • The Yankees are an impressive 22-14 SU on the road this season and 8-1 SU in their last nine games away from Yankee Stadium.
  • Trent Grisham is taking a six-game hitting streak into action Friday and is -160 to extend that streak.
  • Paul Goldschmidt has exceeded 1.5 hits + runs + RBIs in four straight games and eight of his last 10. He’s +100 to cover that line again.
  • Weathers has recorded 18 outs or more in three straight starts and four of his last five. He’s around -150 to record over 17.5 outs.