The Toronto Blue Jays try to stay hot with Dylan Cease on the mound as they look to lock up their first series win since March, and the latest Blue Jays vs. Brewers odds tilt in Toronto’s favour thanks to a strong starter matchup and a struggling Brewers lineup. Milwaukee arrives still searching for consistency after a six‑game slide, while the Jays carry fresh momentum from a 13‑hit, nine‑run effort in the series opener.
Blue Jays vs. Brewers best bet
F5 moneyline – Blue Jays: -129 @ Pinnacle
F5 moneyline – Blue Jays
Toronto has a major starting pitching advantage in this contest with Cease on the mound, so backing it on the F5 moneyline makes sense in this spot against the struggling Brewers.
Backing the Blue Jays on the full-game moneyline at -120 also appears to hold value, but Toronto’s shaky bullpen makes it worth the extra juice to play Toronto only while Cease is still in the game. Toronto relievers own an ugly 4.54 combined ERA across 79 1/3 innings, with opponents hitting a lofty .261 against them to this point in the season.
Always be sure to shop around and find the most favourable odds at the best MLB betting sites.
Blue Jays vs. Brewers odds
| Blue Jays moneyline odds | -120 |
| Brewers moneyline odds | +100 |
| Run line odds | Blue Jays -1.5 (+140), Brewers +1.5 (-165) |
| Game total | Over 7.5 runs (-105), Under 7.5 (-115) |
| Date/time | April 15, 7:40 p.m. ET |
Betting the Blue Jays (7-9 SU, 5-11 ATS, 9-7 o/u)
The Blue Jays halted a two-game slide with a 9-7 win in extra innings in the series opener with Milwaukee on Tuesday night. They managed 13 hits in the contest, with nine different players contributing, which is a positive sign following the club’s offensive struggles to open the season.
Bettors should be aware of Toronto’s extensive injury report (see below), which is without a doubt a major reason why this team has struggled out of the gate.
A win on Wednesday would guarantee the Blue Jays their first series win since their season-opening three-game sweep of the Athletics.
Betting the Brewers (8-8 SU, 9-7 ATS, 10-6 o/u)
After an impressive 8-2 start to the season, the Brewers now find themselves mired in a six-game losing streak to fall back to the .500 mark. The losing streak is Milwaukee’s longest skid since June 2023.
But like Toronto, putting seven runs on the board on Tuesday was an encouraging sign after the club managed just 12 runs over its previous five games. It’s still disappointing, though, that the team took a 4-2 lead into the final three innings before squandering seven runs.
Milwaukee’s 10-6 over/under record out of the gate makes it one of the better “over” plays in the league to this point.
Probable starting pitchers
Toronto: RHP Dylan Cease (0-0, 2.45 ERA, 1.43 WHIP, 15.95 K/9)
Cease has been outstanding through his first three starts with Toronto, holding the opposition to two earned runs or less in each of those outings while striking out 26 batters over 14 2/3 innings.
In a small sample size, the right-hander ranks in the 93rd percentile in average exit velocity (84.4 mph), 98th percentile in whiff rate (42.3%), 96th percentile in strikeout rate (38.8%), and 93rd percentile in hard-hit rate (22.6%).
In 61 career at-bats against Cease, Milwaukee’s current roster has managed just a .230/.309/.311 slash line with a .620 OPS. No one on the roster has ever homered off the righty.
Milwaukee: RHP Chad Patrick (1-0, 0.73 ERA, 1.38 WHIP, 5.11 K/9)
Patrick will be making his third start of the season after last making a relief appearance on Friday against the Washington Nationals.
The right-hander was good in his first two starts of the season, holding the Chicago White Sox to one run over 4 1/3 innings and the Kansas City Royals scoreless over five innings of work.
Patrick does own a 3.72 xERA through three outings this season and an ugly 46.2% hard-hit rate, suggesting he’s been relatively lucky to open the season.
The Blue Jays can expect a healthy diet of cutters and sinkers from the 27-year-old hurler.
Notable injuries
The following notable players on the injured list for the Blue Jays:
- F Anthony Santander (shoulder)
- P Cody Ponce (knee)
- C Alejandro Kirk (thumb)
- P Trey Yesavage (shoulder)
- P Jose Berrios (elbow)
- P Shane Bieber (elbow)
- P Yimi Garcia (elbow)
- P Bowden Francis (elbow)
- OF Addison Barger (ankle)
- OF George Springer (toe)
C Tyler Heineman is also day-to-day with back spasms.
The following notable players are on the injured list for the Brewers:
- OF Jackson Chourio (hand)
- 1B Andrew Vaughn (hand)
- P Quinn Priester (wrist)
- Christian Yelich (hamstring)
P Kyle Harrison is also DTD with knee and wrist issues.
Weather
With rain in the forecast, the retractable roof in Milwaukee will very likely be closed for this game.
Blue Jays vs. Brewers betting trends
- The Blue Jays have hit the F5 team total under in 13 of their last 16 games.
- The Brewers are 0-6 SU and 1-5 on the run line in their last six games.
- The over is 4-0 in Toronto’s last four games.
- Milwaukee is 8-5 against American League opposition this season.
Blue Jays vs. Brewers player prop trends
- Brewers catcher William Contreras has hit safely in nine straight games and is -175 to extend that streak.
- Blue Jays outfielder Jesus Sanchez is riding a six-game hitting streak into action. He’s -165 to extend the streak.
- Blue Jays outfielder Daulton Varsho has recorded over 1.5 hits + runs + RBIs in five straight games and is -105 to make it six straight games.
- Brewers infielder Jake Bauers has homered in two straight games and in three of his last four. He’s +450 to go deep Wednesday.
- Brewers catcher Gary Sanchez has homered in back-to-back games and is +430 to go deep.
