After a thrilling opening round to the 2025 NFL Playoffs, the action is set to return this weekend for the Divisional Round. With four teams remaining in each conference as they look to get one step closer to Super Bowl glory, this weekend’s matchups are must-see.
With the stakes at an all-time high, the only way they could get any higher is by getting some skin in on the games with our Divisional Round best player prop bets. Below, we’ve highlighted the best prop bets available for the Divisional Round so you can boost your bankroll while watching the intense battles on the gridiron unfold in real-time.
Don’t wait, place your next winning wager with our NFL Playoffs Divisional Round best prop bets this weekend and hit paydirt on these can’t-miss matchups.
- Bo Nix Over 20.5 Passing Completions (-115)
- Cooper Kupp Anytime Touchdown Scorer (+300)
- C.J. Stroud 30+ Yard Longest Pass Completion (-155)
- Kyren Williams Over 9.5 Receiving Yards (-110)
Bo Nix Over 20.5 Passing Completions (-115)
After getting a week of R&R after clinching a well-deserved top spot in the AFC Playoff bracket, look for second-year quarterback Bo Nix to let the pigskin fly against the Buffalo Bills, completing Over 20.5 passes in their Divisional Round matchup.
A steady hand in the pocket, Nix plays smart, calculated football that allows him to make easy passes, diminishing the risk of turnovers. While the checkdown may not be the sexiest play in football, Nix and the Broncos have turned it into an art, generating plenty of YAC on each successful completion. With an efficient and methodical game plan, look for Nix to have no trouble mitigating risk, and keeping his passes short and to the chest of his most reliable receiving options.
Nix has had no trouble racking up completions throughout the 2025 NFL season, having averaged 22.8 completions per game. Getting hot at the perfect time, Nix also finished the regular season completing Over 20.5 passes in six of his last seven games played, with the lone outlier coming in a Week 18 route of the Chargers that saw him attempt a season-low 23 pass attempts.
While the Bills may have led the NFL in completions allowed per game in the regular season, look for Nix to buck this trend as he darts Over 20.5 completions in front of his home crowd, providing his Broncos with a great shot of reaching the AFC Championship Game as a result.
Bo Nix Over 20.5 Passing Completions
Cooper Kupp Anytime Touchdown Scorer (+300)
In the regular season, it was Jaxon Smith-Njigba that commanded the spotlight in an All-Pro season with the Seattle Seahawks, but look for former Super Bowl MVP Cooper Kupp to reclaim some of the limelight as he scores a touchdown in this weekend’s postseason clash with the San Francisco 49ers.
While he only hit paydirt twice during the regular season, don’t think that means Kupp isn’t still a dangerous threat near the end zone. With the most NFL Playoff experience of any Seahawk player, look for the former-Triple Crown winner to receive ample targets as he looks to set the tone for his team in a must-win clash with their division rival.
Since Week 13, Kupp has led the Seahawks in red zone targets, notching at least one target in each game played in that span. With his presence featured heavily near the goal line, Kupp may squeak through the cracks of the 49ers defence as they pay ample attention to JSN, connecting with quarterback Sam Darnold for a big play in the end zone.
One of the best playoff performers of his era, look for Kupp to show the NFL world he’s still got some gas in the tank as he scores a touchdown against the 49ers this Saturday.
Cooper Kupp Anytime Touchdown Scorer
C.J. Stroud 30+ Yard Longest Pass Completion (-155)
Hot off the heels of a shaky postseason performance on the road against the Pittsburgh Steelers, look for Houston Texans quarterback C.J. Stroud to shake off the nerves from his last start and put on a great performance against the New England Patriots, highlighted by a 30+ yard completion during the Divisional Round.
Never shy to throw the deep ball, Stroud has built a name for himself as one of the top deep ball passers in the NFL. Often working in tandem with his star wide receiver, Nico Collins, Stroud does a fantastic job at firing the ball deep downfield and connecting for big gains at a moment’s notice. Over his last six games, Stroud has completed 30+ yards five times, demonstrating his consistency on deep passing downs.
With his team needing a star performance from their franchise quarterback, bank on Stroud to get the job done, providing his team with several big plays, including a deep ball completion of 30+ yards against the Patriots.
C.J. Stroud 30+ Yard Longest Pass Completion
Kyren Williams Over 9.5 Receiving Yards (-110)
Capping off the Divisional Round with a highly-anticipated showdown between NFC squads, the Los Angeles Rams will take on a motivated Chicago Bears squad that hopes to make their first NFC Championship Game since 2010. While both sides are hungry to continue pushing toward the Super Bowl, look for Rams running back Kyren Williams to make an impact in the passing attack as he racks up Over 9.5 receiving yards.
A reliable dual-threat back, Williams is as versatile as they come. Possessing a terrific blend of shiftiness and strength, Williams is a handful for any defender to bring down in the open field. Set to take on a scary Bears defensive front, look for Matthew Stafford to have less time in the pocket to take deep shots downfield, instead opting to make short checkdowns to his receivers, with an emphasis on his starting tailback, Williams.
While he isn’t as prominent in the Rams’ passing game as other backs across the league are within their respective teams’ game plan, when given the rock, Williams tends to deliver. Over his last six games played, both in regular and postseason play, Williams has had Over 9.5 receiving yards in each game played, averaging 19.1 yards per game in that span. Additionally, Williams may only need one target to get the job done with this prop bet, having tallied an average of 7.8 yards per reception throughout the 2025 regular season.
Possessing big-play potential, and facing a Bears defence that resided in the bottom-half of the NFL in total running back receiving yards, receptions, and yards per reception allowed in 2025, hammer Williams to easily eclipse the line set for him as he cruises to Over 9.5 receiving yards in the Divisional Round.