One of the most fun and exciting ways to get some skin in on the NFL is through player props, and that’s why we’ve compiled our best bets and expert predictions so you can stuff your bet slip full of winning wagers in Week 6.
Below, we’ve highlighted our best NFL Week 6 player prop bets, taking a deep dive into each pick and providing facts and analysis to help you understand why these are the best bets available for this Sunday’s NFL odds.
Don’t wait, head to your favourite NFL betting site, lock in your next winning wager today with our best NFL Week 6 player prop bets and get ready to see your bankroll skyrocket before Sunday Night Football kicks off.
- Isaiah Likely Over 4.5 Receptions
- Ashton Jeanty Over 28.5 Receiving Yards
- Patrick Mahomes Over 1.5 Passing Touchdowns
Isaiah Likely Over 4.5 Receptions
Kicking things off with a safe player prop that’s sure to have you in the green this weekend, bank on New York Giants tight end Isaiah Likely to continue his breakout season as he hauls in Over 4.5 receptions against the New Orleans Saints.
Through the first five games of the 2026 NFL season, Likely has been a consistent producer within the Giants offence. Having grabbed Over 4.5 receptions in four of his five games played, including an 11-reception performance in Week 5 against the Washington Commanders, it’s become clear that Likely is one of the favourite targets of quarterback Jameis Winston.
Facing a Saints defence that’s not only struggled defensively, but specifically in guarding opposing tight ends as they enter Week 6 allowing the fourth-most receptions to tight ends in the NFL, this has set the stage for a big performance for Likely.
Back Likely to continue tracking on career-best paces, grabbing a plethora of targets, and helping you cash in on the early window this Sunday as he hauls in Over 4.5 receptions against the Saints.
Ashton Jeanty Over 28.5 Receiving Yards
One of the top young, dynamic rushers in the NFL, look for Las Vegas Raiders running back Ashton Jeanty to make an impact as a receiver this weekend as he tallies Over 28.5 receiving yards against the Buffalo Bills.
Taking on one of the NFL’s most explosive offences, the Raiders are going to need to bring their A-game to go toe-to-toe with Josh Allen and company in Week 6. Having steadily produced an abundance of all-purpose yards this season, Jeanty has truly begun to shine as a pass-catching back.
Through the first five weeks of the season, Jeanty has finished four of his five games played with 35 or more receiving yards. With his current receiving yardage line set at 28.5, this is a mouth-wateringly good look for any savvy bettor.
Additionally, while the Bills offence has been gangbusters to this point in the season, they’ve had their shortcomings on the defensive end, primarily when it comes to defending running backs in the passing game. Allowing the second-most receiving yards to running backs in the NFL this season, Jeanty is primed to torch the Bills in the passing game, quickly surpassing Over 28.5 receiving yards in Week 6.
Hammer Jeanty to continue cementing himself as an elite back, reeling in Over 28.5 receiving yards against the Bills as he provides valuable offence for his squad in what’s sure to be a barnburner this Sunday.
Patrick Mahomes Over 1.5 Passing Touchdowns
Rounding out our best NFL Week 6 player prop bets, you can never go wrong betting on the arm of the NFL’s golden boy, Patrick Mahomes. Set to take on a winless Los Angeles Chargers squad, look for Mahomes to light up the scoreboard in a pivotal AFC West clash, throwing Over 1.5 passing touchdowns in the game.
With his Kansas City Chiefs team once again looking like Super Bowl contenders, Mahomes has been on a tear to begin the 2026 season. Sporting an undefeated record through their first four games of the season, coming off of a bye, Mahomes is sure to be well-rested and motivated to take it to his division rival in Week 6.
Having passed for Over 1.5 touchdowns in all four games played this season, Mahomes has connected with six different receivers in the end zone this year. Showing his versatility and elite field vision, Mahomes has no trouble locating the best option on the field and delivering the ball firmly into the chest of his receivers for big gains.
Taking on a Chargers defence that’s allowed two or more passing touchdowns in two of their last four games, bank on Mahomes to deliver multiple end zone strikes, pulling away with the lead, and cashing out your bet slips with a big win as he records Over 1.5 passing touchdowns.
