We’re officially a quarter of the way through the 2026 NFL season and we’ve begun to see the contenders seperate themselves from the pretenders, but that doesn’t mean the oddsmakers know best. After scanning the latest NFL odds and betting lines, we’ve compiled the best Week 5 underdog picks against the spreads to help you win big on all the action this Sunday.
Head to your favourite NFL betting site and tail our Week 5 underdog picks against the spread to gain a competitive edge over the books and score a major boost to your bankroll.
- CLE Browns +2.5
- LV Raiders +3.5
- NY Giants +3.5
Browns +2.5
Somewhat shockingly, the 3-1 Browns are underdogs heading into a Week 5 road clash against the New York Jets. With the Jets having lost three straight games while the Browns have been red hot, this seems like a completely mispriced line.
The Browns have been one of the best underdogs to back across the NFL this season, as they have had the odds stacked against them by oddsmakers in all four games played this season. With a 75% cover/win rate as underdogs, the Browns are primed to continue this sensational upset streak rolling against a Jets team that has been mediocre in all aspects this season.
Hammer the Brownies to pull out another upset as they escape from East Rutherford with a win, covering the spread against the Jets, and continuing their push for their first AFC North title in franchise history.
Raiders +3.5
Hot off the heels of a nail-biter against the AFC powerhouse Kansas City Chiefs, the Las Vegas Raiders have proven themselves as a legitimate playoff threat in 2026. Set to travel to Foxborough to take on the defending conference champions, bank on the Raiders to get back on track as they duel with the New England Patriots.
While the Patriots were able to shock the NFL world with a massive upset over the Buffalo Bills in Week 4 while shorthanded, don’t expect lightning to strike twice as they see themselves returning to their early-season struggles against the Raiders.
With the Patriots offence still incredibly streaky, it’s hard to trust them week to week. Facing a Raiders defence that has been among the league’s elite this season, expect the Pats offence to look out of sorts again as it struggles to generate big plays against the Raiders’ hard-nosed pass rush and solid downfield coverage.
At +3.5, the Raiders are a great bet to cover the spread on the road, improving to 5-0 ATS, and further cementing themselves as a squad to watch in 2026.
Giants +3.5
Rounding out our Week 5 underdog picks against the spread, bank on the New York Giants to prevail in an NFC East tilt against the Washington Commanders, covering the spread as 3.5-point underdogs.
With the Commanders dealing with a plethora of injuries to key contributors on both sides of the ball, this upcoming clash is sure to bring more of the same frustrations and limitations that have plagued them over the first four weeks of the season. Even if quarterback Jayden Daniels is back to full strength and ready to play come Sunday, his constant injury concerns and sporadic play will fall right into the hands of a rough-and-tumble Giants defence.
Look for the G-Men to keep the Commanders on their back foot all game long, abusing them with high-end offensive talents like Malik Nabers, Isaiah Likely, and Cam Skattebo en route to yet another spread covered, improving their ATS record to 4-1. Being spotted a generous 3.5 points, hammer the football Giants to expose the Commanders on the road, racking up their fourth win of the season, and making an aggressive push for a division title early on this season.
