Best NFL Week 2 Underdog Picks Against the Spread

Joe Burrow, Cincinnati Bengals, 2026 NFL Season

Nothing quite beats the feeling of pulling a fast one on the oddsmakers and scoring a win off an underdog pick. That’s why we’ve highlighted the best NFL Week 2 underdog picks against the spread so you can win big while backing a squad to secure the upset on NFL Sunday.

Don’t wait, head to your favourite NFL betting site, load up your bet slip with the latest NFL odds, and get ready to beat the books with our best Week 2 underdog picks against the spread.

  • Minnesota Vikings +4.5 (-110)
  • Cincinnati Bengals +2.5 (-105)
  • New York Jets +3.5 (-115)

Vikings +4.5

Hot off the heels of their thrilling comeback victory against the Green Bay Packers, the Vikings have an opportunity to claim the top spot in the NFC North as they take on the Chicago Bears at Soldier Field.

With a stellar defence that excels at generating turnovers and an explosive offence that can generate big gains on any down, look for them to cover the spread this Sunday. While the Bears offence looked superb in Week 1 against the Carolina Panthers, they’ll have a much harder time generating the same offensive output against a far better defence.

Look for the Vikings to go punch-for-punch with the Bears, matching their offensive output, and giving themselves a legitimate shot to win thanks to their stellar defence, covering the spread to secure you a winning payday in Week 2.

Minnesota Vikings +4.5

-110

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Bengals +2.5

Beginning to look more like the team the NFL world fell in love with a few seasons ago, the Bengals were firing on all cylinders in Week 1 in their victory over the Tampa Bay Buccaneers. Taking on a tough test against the Houston Texans in Week 2, look for the Bengals to put their opponents on upset watch as they cover the short point spread this Sunday.

While the Texans certainly should be feared for their formidable defence, the Buffalo Bills put on a clinic in Week 1, dropping 36 against the Lone Star State squad. With some chinks in the armour beginning to show, this has set the stage for the Bengals to utilize their high-octane passing attack to generate points in droves, jockeying for the lead throughout the contest.

As they near plus-money territory, there’s plenty of value in backing the Bengals to upset the Texans, as they have a real chance to improve to 2-0 and kickstart their 2026 campaign.

Cincinnati Bengals +2.5

-105

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Jets +3.5

Not a team known for their long list of accolades and success, it may be the dawn of a new day in the Meadowlands as the New York Jets have a fantastic opportunity in front of them to improve to 2-0 for the first time since 2015.

Set to take on a Green Bay Packers squad that seems out of sorts amidst shaky playcalling, injuries, and off-field issues, the Jets are primed to capitalize at home over their faltering opponents. While the Packers still possess some upside, look for the Jets well-rounded secondary to limit the passing-heavy attack of their opponents, keeping the score close, and covering the spread in the process.

Buy-in on the Jets early this year, backing them to cover the spread against the Packers, and secure a cheeky win over the oddsmakers with this expert ATS pick.

New York Jets +3.5

-115

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