Blue Jays vs. Angels Predictions, Picks, and Odds for April 21, 2026

Los Angeles Angels shortstop Zach Neto (9) goes back to third against the Seattle Mariners during the fourth inning at Angel Stadium

The Toronto Blue Jays will look to build on their series-opening win when they face the Los Angeles Angels again on Tuesday night in Anaheim, and this Blue Jays vs. Angels prediction spot sets up nicely for a close game with value on the player props market.

Blue Jays vs. Angels prediction

Zach Neto over 0.5 walks: +175 @ Bet99

Neto to draw a walk

+175

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Wagering on a player to draw a walk isn’t the sexiest bet, but there’s enough data to suggest this is a very strong Blue Jays vs. Angels prediction on Tuesday night.

Neto has drawn a walk in exactly 50% of his games this season, making him one of the most disciplined players at the plate. His 16.1% walk rate ranks him in the 89th percentile this season, and he’s been walked in three straight games, including once last night by the Blue Jays.

At +175 odds, Bet99 is implying Neto has 36.3% implied odds to walk in this game, making it a very shrewd bet given his 50% tendency to draw a walk in every game this season.

Additionally, Neto has some incredible career stats against Corbin, going 5-for-11 with three extra-base hits, including a home run. Corbin knows Neto has his number heading into this contest, so bettors can expect him to pitch carefully to the Angels shortstop, thus increasing the chances of a walk even further.

Be sure to always shop around for the most favourable odds at the best MLB betting sites before locking in your wagers.

Blue Jays vs. Angels odds

Blue Jays moneyline odds-105
Angels moneyline odds-115
Run line oddsAngels -1.5 (+175), Blue Jays +1.5 (-210)
Game totalOver 9 runs (-120), Under 9 runs (+100)
Date/timeApril 21, 9:38 p.m. ET
Odds courtesy of bet365.

Betting the Blue Jays (9-13, 7-15 ATS, 11-11 o/u)

The Blue Jays will be looking for a third straight win after claiming a 5-2 win in the series opener with Los Angeles on Monday night.

Right-hander Dylan Cease struck out 12 batters over five innings, and Vladimir Guerrero Jr. had three hits, including a two-run homer to help lift Toronto to the victory.

Perhaps more importantly, Toronto’s beleaguered bullpen pieced together four scoreless innings to close out the game, culminating in closer Jeff Hoffman earning his third save of the season.

Betting the Angels (11-13 SU, 14-10 ATS, 12-12 o/u)

The Angels will be looking to avoid a fourth straight loss on Tuesday after falling to Toronto in the series opener.

Los Angeles has managed to score just four runs over its last three contests, but Tuesday presents as an excellent opportunity for the team to break out offensively against a veteran southpaw. The Angels have a .753 team OPS against lefties this season, which ranks as the ninth-best in baseball, to go along with a .351 on-base percentage (third in majors).

Los Angeles is averaging 4.9 runs per game this season (10th in majors) while allowing 4.5 per game (15th in baseball).

Probable starting pitchers

Toronto: LHP Patrick Corbin (0-0, 4.66 ERA, 1.24 WHIP, 8.38 K/9)

Corbin will be making his third start for the Blue Jays after signing with the team earlier this month in the wake of several injuries to starting pitchers.

The southpaw surrendered one run on four hits while striking out six the last time he took the hill against the Milwaukee Brewers, a much better outing than his initial start for the Blue Jays, when he yielded four runs on six hits over four innings.

Corbin owns an ugly 7.91 xERA and .288 xBA in a small sample size, although his 4.9% walk rate is elite, ranking in the 89th percentile this season.

Los Angeles: RHP Jack Kochanowicz (2-0, 3.47 ERA, 1.24 WHIP, 6.94 K/9)

Kochnaowicz, a sinkerball pitcher, boasts an elite 57.6% ground-ball rate, which ranks in the 91st percentile in the majors this season. He throws the pitch very hard, averaging 96 mph, while also relying on a changeup, four-seamer, and slider for success.

Like Corbin, his xERA (5.08) and xBA (.249) aren’t impressive, and his chase rate (25.3%) ranks in the 20th percentile in MLB this season.

Kochanowicz surrendered three runs on four hits over 6 2/3 innings to the New York Yankees the last time he took the mound.

Notable injuries

The following players are on the injured list for Toronto:

  • OF Anthony Santander (shoulder)
  • P Cody Ponce (knee)
  • C Alejandro Kirk (thumb)
  • P Trey Yesavage (shoulder)
  • P Jose Berrios (elbow)
  • P Shane Bieber (elbow)
  • P Yimi Garcia (elbow)
  • P Bowden Francis (elbow)
  • OF Addison Barger (ankle)
  • OF George Springer (toe)

The following players are on the injured list for the Angels:

  • P Kirby Yates (knee)
  • P Ben Joyce (shoulder)
  • P Alek Manoah (finger)
  • P Robert Stephenson (elbow)
  • P Grayson Rodriguez (shoulder)

C Travis d’Arnaud is day-to-day with a foot injury.

Weather

Forecasts are calling for temperatures around 17 C with a 40% chance of showers this evening in Anaheim. Winds will be light and not play a factor.

  • The under is 6-1 in the Angels’ last seven games.
  • The Angels have covered the run line in seven of their last nine games.
  • The Angels have hit the team total under in 15 of their past 22 home games.
  • The Blue Jays have hit the F5 team total under in 18 of their past 24 games.
  • Kochanowicz has walked two or more batters in 13 straight appearances dating back to last season. He’s -205 to walk over 1.5 batters on Tuesday night.
  • Angels outfielder Jorge Soler has hit safely in four straight games and eight of his last 10. He’s -165 to get a hit.
  • Angels outfielder Jo Adell has struck out at least once in seven straight games and is -185 to extend that streak.
  • Angels shortstop Zach Neto has drawn at least one walk in three straight games and in 50% of his games this season. He’s +175 to earn a walk.