While it may not be on primetime, there’s no doubt what matchup is the game of the week on Sunday as one of the NFL‘s biggest rivalries is renewed as the Buffalo Bills square off against the Kansas City Chiefs. With no love lost between these two AFC contenders, this matchup will not only have significant playoff implications but will also be as personal as it gets in what’s set to be a classic in Week 9.
Ahead of this competitive clash, you can win big and get some skin in on the game with my Bills vs. Chiefs best bet, the Chiefs to cover the two-point spread as favourites.
Bills vs. Chiefs Best Bet: Chiefs to Cover Spread
KC Chiefs -2
In what’s projected to be a closely contested tilt between two of the top Super Bowl contenders in the AFC, the Chiefs are in a prime position to take home the win over the Bills in Week 9.
Set to make use of their home-field advantage, the Chiefs have won their last four games at Arrowhead Stadium in convincing fashion. And they’ll now play host to a Bills squad that has been unable to maintain elite play. The Chiefs are simply the hotter team, possessing key advantages over their opponents.
The passing game is critical to both teams’ success, but there’s no doubt which side has the superior firepower. While you can argue who’s the better quarterback between Josh Allen and Patrick Mahomes, what’s not up for debate is who has the better receiving corps —a significant edge in favour of KC. With no true established number-one receiver for the Bills, they’ll struggle to compete with the talents of Travis Kelce, Xavier Worthy, and Rashee Rice.
On the defensive side of the ball, these squads are evenly matched. Still, at the line of scrimmage, the Chiefs defensive line now has the edge after the Bills announced they’ll be without star defensive tackle Ed Oliver indefinitely due to a torn left biceps.
Set to pull out the victory in what’s sure to be an NFL Sunday thriller, bank on the Chiefs to cover the slim two-point spread as favourites, extending their win streak to four games, and sending you into Sunday Night Football with a boosted bankroll in Week 9.
Bills vs. Chiefs Betting Trends
- In the regular season, the Bills have won four consecutive games against the Chiefs. In the postseason, the Chiefs have won the past four meetings.
- In their last eight head-to-head games (both REG and PST), the Bills and Chiefs have combined for over 51 total points six times, averaging 55.25 points per matchup since the 2021 playoffs.
- The Chiefs are a perfect 3-0 against the spread as home favourites in 2025.
- Coming off a win, the Bills are 1-3 against the spread this season.
Top Player Props to Watch for Bills vs. Chiefs Week 9
- QB Josh Allen Under 234.5 Passing Yards (-110) – Has failed to exceed this mark in five of his last six starts.
- RB James Cook Over 79.5 Rushing Yards (-110) – Has exceeded this stat line in five of his last six games played.
- WR JuJu Smith-Schuster 20+ Receiving Yards (+145) – Has hit this mark in five of his last six games played.
- QB Patrick Mahomes 3+ Passing Touchdowns (+230) – Has thrown for 3+ touchdowns in three of his last four games.
Bills vs. Chiefs Injury Report Week 9
Bills
- LB Shaq Thomspon – Questionable
- K Matt Prater – Questionable
- WR Joshua Palmer – Questionable
- RB Ray Davis – Questionable
- DT DaQuan Jones – Questionable
- DT Ed Oliver – IR
Chiefs
- RB Isaiah Pacheco – Questionable
- WR Hollywood Brown – Questionable
- T Josh Simmons – Questionable
- G Trey Smith – Questionable