Our Blue Jays vs. Yankees predictions for Wednesday will target the Blue Jays salvaging a series split as heavy underdogs with Trey Yesavage on the mound, who’s quickly honed a strong reputation as a big-game pitcher.
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Blue Jays vs. Yankees Prediction: Toronto Blue Jays Moneyline (+145)
Given the strength of the opposing starters they have faced, it does feel as though the Blue Jays lineup has heightened its level of play thus far in the series. They have hit .262, generated ten runs in two games, and have felt to have a heightened competitiveness in the batter’s box.
Getting zero wins from the two games certainly hurts, after some strong ninth-inning rallies following blow-ups from the pitching staff. Offensively, it seems reasonable to believe the Blue Jays can stick with a strong process to find some success against a high-quality arm in Cam Schlittler, while with Yesavage on the mound, any potential runs could be much more meaningful.
Yesavage has pitched to a 1.40 ERA over 19 and 1/3 innings this season, and batters continue to struggle to manage quality contact against his ultra-high release point. He’s been hard-hit just 19.6% of the time, which ranks in the 99th percentile among MLB pitchers this season.
While command remains a concern for Yesavage, he’s more consistently trusted his stuff to limit meaningful contact this season and seemingly lived with potential outcomes of balls left in the middle of the plate, which seems to be the right idea given how batters struggle to see his strong stuff.
Blue Jays vs. Yankees odds
| Blue Jays Moneyline Odds | +145 |
| Yankees Moneyline Odds | -170 |
| Run Line Odds | Blue Jays +1.5 (-150), Yankees -1.5 (+125) |
| Run Total | Over 7.5 runs (-115), Under 7.5 runs (-105) |
| Date/Time | May 20, 5:05 p.m. ET |
Odds courtesy of bet365.
Betting Toronto Blue Jays
It feels like the upcoming stretch of games will indicate whether the early part of this season is simply a lethargic start after a heartbreaking World Series loss, or proof that Toronto had too many bats overachieve last season and was due to come down to earth.
Last season, it was the explosive offensive series in Sacramento beginning on May 29th that marked the clear turning point for the team offensively. As we saw last season, there is still time for the Blue Jays to turn it around, but to this point, MLB pitching has generally seemed to adjust to their disciplined offensive process effectively, and now the team needs to prove it can make some changes to get it going at the plate.
As we have discussed, it has been a solid start to this series for the Blue Jays from an offensive perspective, particularly considering the way Will Warren and Ryan Weathers had fared versus other opponents this season. The Blue Jays fared very well versus Cam Schlittler last season, but the 2026 version of the young righty does appear to offer meaningful improvements.
As we discussed yesterday, the Blue Jays’ bullpen holds respectable results overall and excellent underlying numbers, but it feels like the strong performances have flown under the radar because they have been in game scripts where Toronto is chasing a deficit.
Toronto’s bullpen has posted an ERA of 4.06 this season, ranking 16th in MLB, but holds an xFIP of 3.35 and a strikeout-minus-walk rate of 16.4%, both of which are among the best in the league. The Blue Jays leaned on top reliever Louis Varland in a less-than-ideal situation Tuesday, but he worked through the eighth with just six pitches and will be prepared to close this one up if needed.
Betting New York Yankees
The totality of the Yankees lineup has continued to show improved discipline this season, after being known as a one-trick pony in previous years with the same core. That discipline played a key role in the outcome of Tuesday’s game, as Ryan McMahon made Dylan Cease pay for a pair of walks to Aaron Judge and Jazz Chisholm.
The Yankees have been the fourth-best team in the league versus right-handed pitching this season with a wRC+ of 114, and have walked 12.3% of the time. It’s scary given the power possessed throughout New York’s lineup and with the short porch in right, but Yesavage should be keen to be aggressive early in counts in this game and live with the outcome.
Given how little hard contact the league has managed off Yesavage, granting free passes to a side that has proven to have much-improved discipline is not the right approach. Yesavage has not allowed a home run this season, and it seems important for him to continue to risk giving one up by attacking the zone.
Schlittler has pitched to a 2.81 xERA and 2.71 xFIP this season. He holds a Stuff+ rating of 113 and struck out 10.2 batters per nine.
