Set to be a fiery competition between two of the most explosive teams in the AFC, the Buffalo Bills will travel south to take on the Jacksonville Jaguars out in Duval County in an NFL Playoffs Wild Card matchup. With both teams’ Super Bowl dreams on the line in this contest, the only way the action can get any better is by placing a bet on the Bills vs. Jaguars.
To help you find the best bets and expert picks for this upcoming playoff affair, be sure to check out our Bills vs. Jaguars betting trends below. Each of these trends highlights each teams strengths and weaknesses, as well as how you can use these statistics to formulate a winning bet slip this Sunday.
Don’t wait, get some skin in the game with our Bills vs. Jaguars betting trends and see how you can win big with these profitable betting trends.
| Betting Market | BUF Bills | JAX Jaguars |
| Moneyline | -120 | +100 |
| Point Spread | -1.5 (-110) | +1.5 (-110) |
| Over/Under | O 51.5 (-110) | U 51.5 (-110) |
Bills 2025 Betting Trends
- Buffalo was less than trustworthy against the spread (ATS) this season, going 8-9 on the year. Even more concerning, when favoured, the Bills went 6-9 ATS in that span.
- While they weren’t the best team when it came to covering the spread, the Bills did live up to the hype as a straight up (SU) pick to win, going 10-5 outright when favoured.
- Since 2019, the Bills have had no shortage of high-scoring playoff tilts, repping an over/under record of 8-4-1.
Bills to win the Super Bowl
Jaguars 2025 Betting Trends
- Tied for the best ATS record in the NFL with the Seattle Seahawks and Los Angeles Rams, the Jaguars went 12-5 against the spread this season.
- The Jaguars have played some of their best football at home this season, posting a sensational 7-1 SU record. Additionally, the Jags were incredibly successful as home underdogs, going 3-1 during the 2025 season.
- In the Trevor Lawrence era, the Jaguars have only made the postseason once, but in both games played in their 2022 run, they covered the spread in each contest.
Jaguars to win the Super Bowl
Bills vs. Jaguars Head-to-Head Betting Trends
- In their last three head-to-head matchups, the Jaguars have beaten the Bills twice. Although the Bills dominated in their previous meeting during the 2024 season, cruising to a 47-10 victory.
- In the same span, Bills vs. Jaguars games have produced low-scoring affairs, with Under 51.5 points in two of their three meetings.
- Historically, these teams have met in the playoffs twice, in 1996 and 2018, with the Jags emerging victorious in both clashes.
Prediction: Jaguars to Cover as Slight Underdogs (+1.5)
Based on the latest 2025 betting trends, the smart money resides with the Jaguars to cover the spread as +1.5 underdogs against the Bills.
While this is as slim a margin as you’re going to find in the 2025 NFL Playoffs, it’s worth backing for a multitude of reasons. With the Bills having struggled to cover the spread overall this season, this has proven to the football world that, while they’re a good team, they’re not a great one. Taking one of the best teams in all of football when it comes to covering the spread, all signs point toward a Jags cover at home this Sunday.
Additionally, the Jaguars are in a great position to win the game outright, much to the dismay of Bills Mafia members North of the U.S. border. With home-field advantage, a superior record, and a history of getting the better of the Bills in head-to-head matchups in the Allen vs. Lawrence era, the Jags are the best bet to make.
Bank on the Jaguars to cover the spread as underdogs as they continue to make their push toward the Super Bowl, as they hope to send Duval into a frenzy by notching their first postseason victory since 2022.