Buccaneers vs. Lions Picks & Predictions on Monday Night Football Week 7

Detroit Lions tight end Sam LaPorta (87) runs against Kansas City Chiefs during the first half at Arrowhead Stadium in Kansas City, Missouri on Sunday, Oct. 12, 2025.

Kicking off an NFL Monday Night Football doubleheader, we’ve got a battle between two of the best teams in the NFC as the Tampa Bay Buccaneers look to make it three in a row as they take on the Detroit Lions from Ford Field.

In this primetime affair between Super Bowl contenders, back the Lions to get the job done at home, securing the win against the Buccaneers on Monday Night Football Week 7.

Lions Moneyline vs. Buccaneers

-275

Monday Night Football Best Bet: Lions to Defend Home Turf

In what’s sure to be a thrilling contest between two explosive offences, look for the Lions to simply be too much to handle for the Buccaneers on Monday Night Football.

Coming off a disappointing performance against the Kansas City Chiefs in Week 6, look for the Lions to bounce back in a big way as they exorcise some demons at the expense of the Buccaneers.

While the Bucs have done a solid job of stopping the run in 2025, look for this trend to change as the dynamic backfield duo of Jahmyr Gibbs and David Montgomery have no trouble stampeding down the gridiron in order to put their team in scoring position. Additionally, the Lions’ passing game is equally as effective with standout talents such as Sam LaPorta and Amon-Ra St. Brown always primed for big outings in marquee matchups.

Bank on the Lions to secure the bounce-back win in a high-scoring shootout, as they use their superior firepower to outscore their opponents. At -275, the Lions are strong favourites to win, making them a safe bet to add to your bet slip ahead of Monday Night Football Week 7.

  • The Buccaneers are 3-1 SU as underdogs in 2025.
  • The Buccaneers are 3-0 ATS as the away team this season.
  • The Lions are 3-0 ATS as favourites in 2025.
  • Since 2023, the Lions are 8-0 SU coming off a loss.

Top Player Props to Watch on Monday Night Football

  • Baker Mayfield Over 243.5 Passing Yards (-120) – Hit in last three games.
  • Rachaad White Over 20.5 Receiving Yards (-110) – Hit in last three games.
  • Jahmyr Gibbs Over 61.5 Rushing Yards (-110) – 83.3% hit rate in 2025.
  • Amon-Ra St. Brown Over 6.5 Receptions (-165) – Hit in last five games.

Monday Night Football Injury Report

Buccaneers

  • WR Emeka Egbuka (Hamstring) – Questionable
  • WR Mike Evans (Hamstring) – Questionable
  • LB Lavonte David (Knee) – Questionable
  • QB Teddy Bridgewater (Illness) – Questionable
  • T Luke Haggard (Shoulder) – OUT
  • RB Josh Williams (Concussion) – OUT
  • WR Chris Godwin (Fibula) – OUT
  • RB Bucky Irving (Foot) – OUT

Lions

  • DT DJ Reader (Back) – Questionable
  • T Taylor Decker (Shoulder) – Questionable
  • DT Alim McNeil (Knee) – OUT
  • CB Terrion Arnold (Shoulder) – OUT
  • RB Sione Vaki (Groin) – OUT
  • S Kerby Joseph (Knee) – OUT
  • G Miles Frazier (Knee) – OUT
  • EDGE Josh Pascal (Undisclosed) – OUT
  • CB Avonte Maddox (Hamstring) – OUT
  • LB Malcolm Rodriguez (Knee) – OUT