One of the best ways to bet on any primetime NFL matchup is with same game parlays. That’s why we’ve compiled our top moneymaking Bills vs. Patriots same game parlay for Sunday Night Football Week 5.
Along with our pre-built parlay, you can also dive deeper into each of my individual picks featured with in-depth expert insight and NFL betting analysis.
Find my Bills vs. Patriots same game parlay using odds from bet365 for Sunday Night Football Week 5 below!
- Buffalo Bills Moneyline
- James Cook Over 80.5 Rushing Yards
- Josh Allen Over 20.5 Pass Completions
Matt’s Bills vs. Patriots Same Game Parlay
Buffalo Bills Moneyline (-400)
An easy pick to make ahead of kick off on Sunday Night Football, the Bills should have no problem picking up the win in this AFC East rivalry matchup. Sporting an undefeated 4-0 record, the Bills have continued to look the part of a Super Bowl contender in 2025.
Taking on an inferior team in the Patriots, the Bills have several matchup edges heading into this clash. Notably, the Bills roster is far more experienced than the youthful Patriots team. Additionally, the Patriots have struggled to maintain consistent play this season, with losses to the Las Vegas Raiders and Pittsburgh Steelers, as well as a nail-biter against the Miami Dolphins. The Patriots simply haven’t shown that they’ve got what it takes to hang with the big dogs of the AFC.
Back the Bills to improve to 5-0 on the season, the first time they’ve started a season with that record since 1991, clinching your same game parlay on Sunday Night Football.
James Cook Over 80.5 Rushing Yards (-110)
Continuing to blossom into one of the best rushers in the NFL, James Cook has been eating up yardage for breakfast this season. Having finished three straight games with over 100 yards rushing, he’s a great bet to rack up over 80.5 rushing yards against the Patriots.
While to their credit, the Patriots have been solid at stopping the run (rank third allowing just 77.5 yards per game) early on this season, they’ve yet to face a back like Cook to this point. With a solid offensive line in front of him, look for the Bills to hand the ball off to Cook routinely throughout the contest, pushing the rock downfield, and quickly eclipsing his rushing yard total to earn you a checkmark on your Bills vs. Patriots same game parlay.
Josh Allen Over 20.5 Pass Completions (-130)
Lastly, you can’t go wrong backing the reigning MVP in a same game parlay, so why not sprinkle in Josh Allen to complete over 20.5 passes against the Pats. Having already achieved this feat twice this season, Allen will look to use his stellar arm to complete easy passes throughout this primetime showdown.
With several reliable playmakers, such as Keon Coleman, Khalil Shakir, and Dalton Kincaid all beginning to hit their strides this season, look for there to be openings in the defence that will be ripe for Allen to exploit, completing passes, and helping secure your +275 payday with our Bills vs. Patriots same game parlay.
Be sure to shop around at the best NFL betting sites in Canada for the best odds on your legs of any created parlay!